Objectives. To provide current national estimates of lesbian, gay, bisexual, and questioning (LGBQ) adolescents’ (grades 9–12) substance use risks.
Methods. The 2015 national Youth Risk Behavior Survey included questions for 19 substance use outcomes covering 15 substances. LGBQ adolescents’ substance use was described and their risk relative to heterosexual adolescents was estimated after controlling for sociodemographic confounders.